The best detection algorithms cannot neglect the feeling of a patient or the trained experience of a clinician. Neurotechnology is a complementor to other advances in healthcare. To ensure that we can improve the quality of life of several patient groups by embracing advanced artificial intelligence (AI) and hardware innovations, we need to place the needs and requirements of patients, caregivers, and medical professionals at the forefront. Extensive behavioral and psychological testing is therefore essential to validate AI algorithms and technological interfaces with the brain - particularly in a home-based environment. We will test and refine our software using biologically realistic simulations of electrically generated vision using virtual reality before stimulating the visual cortex in people who are blind, and will conduct behavioral tasks of daily living tasks such as walking in cluttered environments, using whole body motion sensing to quantify behavior. We will use EEG and other neuroimaging measures to monitor seizures, stress and psychological responses to the closed-loop system for seizure prevention.